For those who are in the medical science area fighting diseases and intoxications on a daily basis, this book intends to bring some of the latest results written to a medical context. For students of chemistry and medical sciences, this book will help shed some light on, for instance, the role of metal ions in the environment of life and how sinister the consequences are of contaminations in the environment, mainly water and soils. Results in the scientific literature in Medical Sciences are seldom read by medical doctors. However, many results in Bioinorganic Chemistry and Biochemistry are straight linked to free radicals production and to some diseases, such as degenerative ones (Alzheimer, Parkinson, Wilson, etc.). Metal ions are now shown in the chemistry literature to play a vital role in these diseases. Therefore, external chemical effects, as well as biochemical (internal) effects have to be considered.


This third volume focuses on the newest information on metal ion contaminations and the influence of some of them in neurological diseases, a subject still not completely understood in the scientific literature so far. The book presents an extensive review on the aluminium forms of intoxication in humans and the role of this metal ion in human pathobiology by presenting live cases experienced in hospitals and discussing similar data; a review on the recent findings of the role of aluminium, zinc and copper in neurological disorders based on the chemical and bioinorganic aspects of these metal ions; a review on the genotoxic effects of the metal ions aluminium, iron and manganese either in vivo and in vitro results; information concerning arsenic and its structural effects on the human erythrocyte and some complementary model studies, and provides a study on coffee cultures in contaminated soils and its influence on human health.

Molecular & Supramolecular Bioinorganic Chemistry: Applications in M

REF: 978-1-62100-624-4
170,00 €Preço
  • Este livro da série "Molecular and Supramolecular Bioinorganic Chemistry: Applications in Medical and Environmental Sciences" , volume III em formato capa dura, pode ser encontrado no site da Nova Science Publishers em:


    Formato Ebook pode ser adquirido em:


    Editors: Ana Lucia Ramalho Mercê; María Ángeles Lobo Recio; Judith Felcman

    Idioma: Inglês

    número de páginas: 241

    Editora: Nova Science Publishers, New York, USA

    Ano: 2013

    Table of Contents: 
    Introduction pp. i-vii 

    Chapter 1: Aluminium intoxications in humans. The past, the present and the future, pp. 1-109 
    (Kenrick Berend, Department of Internal Medicine, St. Elisabeth Hospital, Curaçao, Netherlands Antilles) 

    Chapter 2: The Role of Aluminum in the Pathobiology of Human Disease, pp. 111-119 
    (Gordon L. Klein, Orthopædic Surgery and Rehabilitation, University of Texas Medical Branch, Galveston TX; Children’s Hospital at Scott and White/Texas A&M University College of Medicine, Temple TX USA) 

    Chapter 3: Some biological aspects of Aluminium (III) – a review, pp. 121-143 
    (Thaís Valéria Barreiros Alves, Ana Lucia Ramalho Mercê and Judith Felcman, Pontifícia Universidade Católicado Rio de Janeiro - Rua Marquês de São Vicente,Rio de Janeiro, Brazil; LEQ - DQ - Universidade Federal do Paraná - UFPR - Centro Politécnico - Jardim das Américas - Curitiba - PR - Brazil) 

    Chapter 4: Genotoxic effects of aluminum, iron and manganese in human cells and experimental systems, pp. 145-166 
    (P. D. L. Lima, R. C. Montenegro and R. R. Burbano, Molecular Biology Laboratory, Center of Biological and Health Sciences, State University of Pará, Belém, Pará, Brazil; Human Cytogenetics Laboratory, Institute Biological Sciences, Federal University of Pará, Belém, Pará, Brazil) 

    Chapter 5: Structural effects of arsenic on the human erythrocyte membrane and molecular models, pp. 167-195 
    (Mario Suwalsky, Cecilia Rivera, Fernando Villena, Carlos P. Sotomayor, Malgorzata Jemiola-Rzeminska, Kazimierz Strzalka, 
    Faculty of Chemical Sciences, University of Concepción, Concepción, Chile; Faculty of Biological Sciences, University of Concepción, Concepción, Chile; Institute of Chemistry, Faculty of Sciences, Catholic University of Valparaíso, Valparaíso, Chile; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland) 

    Chapter 6: Aluminium soil contamination: its effects on coffee and its role in human health, pp. 197-216 
    (J. Armando Muñoz-Sánchez and S.M. Teresa Hernández-Sotomayor, 
    Unidad de Bioquímica y Biología Molecular de Plantas, Centro de Investigación Científica de Yucatán (CICY), Col. Chuburná de Hidalgo, Merida, Yucatan, Mexico) 

    Index pp. 217-234



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